Broad spectrum CBN is used for several reasons. It regulates several body functions, including immune response, vascular function, and skin health. It also has neuromodulatory properties and is an anti-inflammatory. It works by binding to vanilloid receptors in the brain, which are responsible for temperature regulation and response to stimuli. Finally, broad spectrum cbn enables CBN to provide a physical relaxation experience without the psychoactive effects.
Anti-inflammatory
Inflammation has been linked to 15 and 20% of cancer deaths worldwide. The presence of inflammatory cells in tumor tissue controls growth, metastasis, and angiogenesis. Studies have shown that nonsteroidal anti-inflammatory drugs can decrease the risk of stomach, colon, and esophageal cancer by 40 to 50 percent.
CBN has been shown to reduce inflammation in animals. However, it is challenging to prove effectiveness in humans. Nevertheless, preclinical studies indicate that CBN may play a role in treating eye diseases, including glaucoma. In addition, CBN is known to lower eye pressure, which may slow the progression of glaucoma.
CBN has also effectively treated sleep disorders, pain, and inflammation. For example, a study conducted in 2017 by Steep Hill Labs found that a 2.5-to-5 milligram dose of CBN was as effective as the pharmaceutical sedative diazepam. The study did not appear in a peer-reviewed journal but showed promise.
Inflammation also causes several different cellular pathways to activate. For example, the intestinal CB1 receptor, or CB1, is highly expressed in the ileum and colon. When DNBS is administered to mice with colonic inflammation, it significantly increases CB1-expressing cells. A study also showed that CB1 receptors protect against experimental colitis. The experimental colitis was induced with 2,4-dinitrobenzene sulfonic acid and a dextran sodium sulfate, which caused the inflammatory response in mice.
Synthetic cannabinoids, including CP55,940, are effective anti-inflammatory compounds, according to in vitro research. Synthetic cannabinoids suppress cytokine production in rheumatoid fibroblast-like synoviocytes and inhibit IL-1b-stimulated immune cell activity.
Further research is needed to understand how cannabinoids affect T-cell-mediated immune responses and inflammatory chemokines. Nevertheless, these cannabinoids are promising novel anti-inflammatory agents. In addition, specific targeting of CB2 receptors holds promise for developing non-psychoactive cannabinoid agonists with anti-inflammatory effects.
Broad-spectrum CBN is an effective anti-inflammatory agent. It is used to treat inflammation and also helps reduce the risk of certain diseases, like arthritis. Researchers have shown that CBN may also have neuroprotective effects and slow the progression of diseases. In addition, it has been shown to decrease the risk of strokes and improve cognitive functions.
In addition to anti-inflammatory properties, CBN can also help improve sleep. A study from 2016 found that CBN can reduce symptoms of arthritis compared to NSAIDs. The researchers noted that the effect on sleeping and pain was significant. Moreover, the study also indicated that cannabis might be helpful for various health problems.
The body’s endocannabinoid system responds to the modest medicinal cannabinoids CBN and CBD. They complement each other in hemp extracts but are distinct in their benefits and interactions in the body. For example, CBD and CBN can help improve mood and relieve stress, nervousness, and pain symptoms.
